The MACS technique helps sort out the apoptotic spermatozoa, those undergoing programmed cell death or with DNA fragmentation, from healthy sperm to get the most viable sperm. The use of high quality sperm in the IVF, ICSI, and IMSI processes helps increase the chance of pregnancy success. Then with the healthier resulted embryo after the fertilization, the risk of miscarriage is reduced.
 

• Those diagnosed with a high sperm DNA Fragmentation Index
• Couples whose IVF, ICSI, and IMSI attempts have not been successful 
• Couples in which the woman has had recurrent miscarriages for unknown reasons
• Couples in which the male spouse is an elderly male but still wants to have children
• Couples wishing to reduce the chance of passing on the genetic damage in sperm to their offspring 
• Couples who want high quality sperm
• Couples who are infertile for no reason