Patients must undergo exophthalmos treatment alongside thyrotoxicosis treatment simultaneously. The patient must see an endocrinologist to keep their hormones at a controlled hormone level in order for successful exophthalmos treatment.

The first stage of exophthalmos treatment involves symptomatic treatment – with symptoms changing every 2-3 months. In cases which double vision, crossed eyes, and eyelid abnormalities occur, steroid medication may be considered.

In most instances, exophthalmos begins to settle approximately 1 ½–2 years after it sets in. Some patients may recover completely or have reduced bulging, while others continue to have substantial bulging. Surgical correction of the eye socket can be carried out by an expert ophthalmologist specializing in orbital and cosmetic eye surgery for cases of substantial bulging due to ineffective treatment.