Low testosterone can be caused by injury to the testes (e.g., trauma, castration,radiation or chemotherapy), testicular infection, hormonal disorders (e.g., pituitary tumors or diseases, high levels of prolactin), or other systemic diseases (e.g., HIV/AIDS, chronic liver and kidney disease too much body fat, and type 2 diabetes and associated obesity). Some medications and several genetic conditions (e.g., Klinefelter syndrome, hemochromatosis, Kallmann syndrome, Prader-Willi syndrome, and mytonic dystrophy) can also cause low testosterone. Many older men have low testosterone levels and, in many cases, the cause is not known.

During a physical exam, your doctor will examine body hair,breast size, consistency and size of the testes, scrotum, penis size, etc. Your doctor will also use blood tests to evaluate if the total testosterone level is within the normal range. To diagnose low testosterone you may need more than one early-morning (7-10 AM) blood test and, sometimes, other tests of the pituitary gland's hormones.

Testosterone replacement therapy can improve men's health in general such as increased sense of mood and well being, increased energy and vitality, and also heightening sexual interest, erectile function, body hair growth, bone density, and muscle mass.There are several methods of testosterone replacement:

• Injections
• Patches
• Gel
• Oral forms

The best method will depend on the cause of the problem, the patient's preference and tolerance, and cost. For long term use of Testosterone replacement, patients will be continuously monitored to achieve the best possible result and prevent risk according to international standard.