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HomeLab Services GuideTests
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Overview
ข้อมูลทั่วไป Specimen
ข้อมูลสิ่งส่งตรวจ Performance
ข้อมูลการทดสอบ Clinical & Interpretation
ข้อมูลทางคลินิก
 
Test Code (รหัสการทดสอบ):
HCGTOTAL
Order Name (ชื่อการทดสอบ):
B-HCG (Beta-Human Chorionic Gonadotropin)
 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain Blood (Red Top) 6 mL, 1 tube
 
Turnaround Time (ระยะเวลารอผล):
Specimen collected to reported within 2 hours 
 
 
Useful For (ประโยชน์การทดสอบ):
Determination of beta human chorionic gonadotropin (β-hCG) in human serum  for the early detection of pregnancy.
 
Methodology (วิธีการทดสอบ):
Chemiluminescent Microparticle Immuno Assay (CMIA)
 
AliasesName (ชื่อเรียกอื่นๆ) :
hCG (Human Chorionic Gonadotropins)
Beta-HCG (Human Chorionic Gonadotropin)
Human Chorionic Gonadotropins (hCG)
 
 
 
Test Code (รหัสการทดสอบ):
HCGTOTAL
Order Name (ชื่อการทดสอบ):
B-HCG (Beta-Human Chorionic Gonadotropin)
 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain Blood (Red Top) 6 mL, 1 tube
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
Serum, minimum volume 1 mL
 
Sub Mission Container (ภาชนะส่งตรวจ):
Plastic vial
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Specimen Type Temperature Time
Serum (keep in original tube) Refrigerated, 2oC to 8oC 8 hours
Serum Refrigerated, 2oC to 8oC 7 days
Frozen, -20oC 12 months
Room Temperature 24 hours
 
 
 
Test Code (รหัสการทดสอบ):
HCGTOTAL
Order Name (ชื่อการทดสอบ):
B-HCG (Beta-Human Chorionic Gonadotropin)
 
Method detail (วิธีการทดสอบ):
Chemiluminescent Microparticle Immuno Assay (CMIA)
 
Schedule (ตารางการทดสอบ):
Tested daily (24 hours)
 
Turnaround Time (ระยะเวลารอผล):
Specimen collected to reported within 2 hours 
 
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
Immunology, Laboratory Department Tel. 13227
 
Specimen Retention Time (ระยะเวลาเก็บสิ่งส่งตรวจ):
5 days
 
 
 
Test Code (รหัสการทดสอบ):
HCGTOTAL
Order Name (ชื่อการทดสอบ):
B-HCG (Beta-Human Chorionic Gonadotropin)
 
 
Clinical Information (ข้อมูลทางคลินิก):
Human chorionic gonadotropin (hCG) is a sialoglycoprotein with a molecular weight of approximately 46,000 daltons. HCG is initially secreted by the trophoblastic cells of the placenta shortly after implantation of the fertilized ovum into the uterine wall. The rapid rise in hCG serum levels after conception makes it an excellent marker for early confirmation and monitoring of pregnancy.

Physiologically, hCG appears to maintain the corpus luteum, thereby allowing synthesis of progesterone and estrogens that support the endometrium. As uncomplicated pregnancies progress, the placenta assumes the production of these hormones. The serum hCG levels increase to a peak concentration, then decrease and plateau. HCG circulates as the intact molecule in the serum of normal women who have an uncomplicated pregnancy. The subunits are cleaved rapidly and cleared by the kidney. The placental hormone, hCG, is similar to luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH). All are
glycoproteins consisting of two noncovalently bound dissimilar subunits, designated alpha and beta, with attached carbohydrate sidechains. The alpha subunits of these glycoproteins are very similar. In contrast, the beta subunit portions determine the biological and immunochemical specificities.  The beta subunits of hCG and LH exhibit considerable homology in amino acid content. Amino acid residues specific for the beta subunit of hCG confer the immunochemical specificity. 

With the availability of sensitive quantitative assays for the measurement of serum β-hCG, it has been shown that hCG levels can be useful in prediction of spontaneous abortions, aiding in the detection of ectopic
pregnancy and multiple gestation.
 
Reference Value (ค่าอ้างอิง):
0 - 5 mIU/mL
 
Clinical Reference (เอกสารอ้างอิง):
Manufacturer’s Reagent package insert Architect  Total β-hCG, Abbott Ireland, Diagnostic Division Lisnamuck Longford Co., Ireland.