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HomeLab Services GuideTests
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Overview
ข้อมูลทั่วไป Specimen
ข้อมูลสิ่งส่งตรวจ Performance
ข้อมูลการทดสอบ Clinical & Interpretation
ข้อมูลทางคลินิก
 
Test Code (รหัสการทดสอบ):
CRU
Order Name (ชื่อการทดสอบ):
Creatinine, Random Urine
 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
Urine, Clean container 
 
Turnaround Time (ระยะเวลารอผล):
Collected specimen to report within 90 min
 
Useful For (ประโยชน์การทดสอบ):
Urinary creatinine, in conjunction with serum creatinine, is used to calculate the creatinine clearance, a measure of renal function.
 
Methodology (วิธีการทดสอบ):
Enzymatic
 
AliasesName (ชื่อเรียกอื่นๆ) :
Creatinine, Random urine
 
 
 
Test Code (รหัสการทดสอบ):
CRU
Order Name (ชื่อการทดสอบ):
Creatinine, Random Urine
 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
Urine, Clean container 
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
Urine , minimum volume 10 mL
 
Sub Mission Container (ภาชนะส่งตรวจ):
Clean container
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Specimen Type Temperature Time
Random urine Refrigerated, 2oC to 8oC 6 days
Frozen, -20oC 6 months
 
 
 
Test Code (รหัสการทดสอบ):
CRU
Order Name (ชื่อการทดสอบ):
Creatinine, Random Urine
 
Method detail (วิธีการทดสอบ):
Enzymatic
 
Schedule (ตารางการทดสอบ):
Tested daily (24 hours)
 
Turnaround Time (ระยะเวลารอผล):
Collected specimen to report within 90 min
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
Chemistry, Laboratory Department Tel. 13224
 
Specimen Retention Time (ระยะเวลาเก็บสิ่งส่งตรวจ):
7 days
 
 
 
Test Code (รหัสการทดสอบ):
CRU
Order Name (ชื่อการทดสอบ):
Creatinine, Random Urine
 
 
Clinical Information (ข้อมูลทางคลินิก):
Creatinine is formed from the metabolism of creatine and phosphocreatine, both of which are principally found in muscle. Thus the amount of creatinine produced is in large part dependent upon the individual's muscle mass and tends not to fluctuate much from day-to-day.  

Creatinine is not protein-bound and is freely filtered by glomeruli. All of the filtered creatinine is excreted in the urine. Renal tubular secretion of creatinine also contributes to a small proportion of excreted creatinine. Although most excreted creatinine is derived from an individual's muscle, dietary protein intake, particularly of cooked meat, can contribute to urinary creatinine levels.

The renal clearance of creatinine provides an estimate of glomerular filtration rate.
 
Reference Value (ค่าอ้างอิง):
30.00 – 161.00 mg/dL
 
Interpretation (การแปลผล):
24-Hour urinary creatinine determinations are principally used for the calculation of creatinine clearance.

Decreased creatinine clearance indicates decreased glomerular filtration rate. This can be due to conditions such as progressive renal disease, or result from adverse effect on renal hemodynamics that are often reversible including certain drugs or from decreases in effective renal perfusion (eg, volume depletion or heart failure).

Increased creatinine clearance is often referred to as "hyperfiltration" and is most commonly seen during pregnancy or in patients with diabetes mellitus, before diabetic nephropathy has occurred. It also may occur with large dietary protein intake.
 
Clinical Reference (เอกสารอ้างอิง):
  1. Manufacturer’s reagent package insert, Architect ® Creatinine (enzymatic), SENTINEL CH.SpA Via Robert Koch, 2 Milan 20152, Italy .
  2. http://www.mayomedicallaboratories.com (Retrieved: 01 Jan 2019)