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HomeLab Services GuideTests
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Overview
ข้อมูลทั่วไป Specimen
ข้อมูลสิ่งส่งตรวจ Performance
ข้อมูลการทดสอบ Clinical & Interpretation
ข้อมูลทางคลินิก
 
Test Code (รหัสการทดสอบ):
F9
Order Name (ชื่อการทดสอบ):
Factor IX activity assay
 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
Blood / Sodium citrate tube (Sodium Citrate 3.2% anticoagulant, Blue top) 3 mL, 1 tube
 
Turnaround Time (ระยะเวลารอผล):
Collected specimen to report within 3 hours
 
Useful For (ประโยชน์การทดสอบ):
Evaluate spontaneous or prolonged bleeding suggestive of a coagulation disorder, Diagnosing hemophilia B (or Christmas disease)
 
Methodology (วิธีการทดสอบ):
Clotting assay
 
AliasesName (ชื่อเรียกอื่นๆ) :
Factor IX Assay
Hemophilia B
Factor 9 Activity Assay
 
 
 
Test Code (รหัสการทดสอบ):
F9
Order Name (ชื่อการทดสอบ):
Factor IX activity assay
 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
Blood / Sodium citrate tube (Sodium Citrate 3.2% anticoagulant, Blue top) 3 mL, 1 tube
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
Citrate plasma, minimum volume 0.5 mL
 
Sub Mission Container (ภาชนะส่งตรวจ):
Plastic tube
 
Rejection Criteria (เกณฑ์ปฏิเสธสิ่งส่งตรวจ):
Hemolysis: Hemoglobin > 500 mg/dL reject
Lipemia: Triglyceride > 1000 mg/dL reject
Icterus: Bilirubin > 26 mg/dL
Other: Clotted specimen will be rejected.
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Specimen Type Temperature Time
Whole blood, Sodium citrate Room temperature, 18oC to 25oC 4 hours
Plasma, Sodium citrate Refrigerated, 2oC to 8oC 4 hours
Room temperature, 18oC to 25oC 4 hours
Frozen, -20oC 2 weeks
Frozen, -70oC 6 months
 
 
 
Test Code (รหัสการทดสอบ):
F9
Order Name (ชื่อการทดสอบ):
Factor IX activity assay
 
Method detail (วิธีการทดสอบ):
Clotting assay
 
Schedule (ตารางการทดสอบ):
Tested Daily (24 hours)
 
Turnaround Time (ระยะเวลารอผล):
Collected specimen to report within 3 hours
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
Hematology, Laboratory Department Tel. 17254
 
Specimen Retention Time (ระยะเวลาเก็บสิ่งส่งตรวจ):
14 Days
 
 
 
Test Code (รหัสการทดสอบ):
F9
Order Name (ชื่อการทดสอบ):
Factor IX activity assay
 
 
Clinical Information (ข้อมูลทางคลินิก):
Factor IX is a single chain vitamin K-dependent glycoprotein which is synthesized in the liver. During coagulation factor IX is converted to the active form, factor IXa, by either factor XIa or the factor VIIa/tissue factor/phospholipid complex. Factor IXa is the catalytic component of the intrinsic factor Xase complex (factor IXa, factor VIIIa, cellular surface and calcium ions) which proteolytically activates factor X to factor Xa. Congenital deficiency of factor IX leads to Hemophilia B (or Christmas disease), which is a inherited disorder that causes from mild to severe bleeding which may follow injury or occur spontaneously. Factor IX deficiencies may also be acquired secondarily due to other diseases such as liver disease and Disseminated Intravascular Coagulation (DIC). Patients receiving oral anticoagulant therapy or with a vitamin K deficiency due to intake or absorption abnormalities will have reduced plasma levels of FIX The lack of factor IX in origin causes hemophilia B or Christmas disease as a cause of mild bleeding to severe bleeding. In addition, the reduction of Factor IX may be caused by liver disease or Disseminated Intranascular Coagulation (DIC) as well Genes that control the formation are on the x-chromosome. Heredity is therefore x-linked recessive incidence in men. Approximately 1: 100,000 symptoms and severity are not isolated from hemophilia A and laboratory tests also found that APTT values For a long time, it is necessary to check the factor assay to help diagnose. Because of different treatments
 
Reference Value (ค่าอ้างอิง):
65 -150 % Activity
 
Clinical Reference (เอกสารอ้างอิง):
  1. Manufacturer’s reagent package insert , Factor IX deficient plasma, Instrumentation Laboratory Company - Bedford, MA 01730-2443 (USA), Instrumentation Laboratory SpA - V.le Monza 338 - 20128 Milano (Italy); 06/2014
  2. https://www.mayocliniclabs.com (Retrieved: 22 Jan 2019)