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Overview
ข้อมูลทั่วไป Specimen
ข้อมูลสิ่งส่งตรวจ Performance
ข้อมูลการทดสอบ Clinical & Interpretation
ข้อมูลทางคลินิก
 
Test Code (รหัสการทดสอบ):
GGT
Order Name (ชื่อการทดสอบ):
GGT (Gamma-Glutamyltransferase)
 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Turnaround Time (ระยะเวลารอผล):
Collected specimen to report within 90 min
 
Useful For (ประโยชน์การทดสอบ):
Diagnosing and monitoring hepatobiliary disease, it is currently the most sensitive enzymatic indicator of liver disease. Ascertaining whether observed elevations of alkaline phosphatase are due to skeletal disease (normal gamma-glutamyltransferase: GGT) or reflect the presence of hepatobiliary disease (elevated GGT). A screening test for occult alcoholism.
 
Methodology (วิธีการทดสอบ):
L-Gamma-glutamyl-3-carboxy-4-nitroanilide Substrate
 
AliasesName (ชื่อเรียกอื่นๆ) :
Gamm GT
GGT
 
 
 
Test Code (รหัสการทดสอบ):
GGT
Order Name (ชื่อการทดสอบ):
GGT (Gamma-Glutamyltransferase)
 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
Serum, minimum volume 0.5 mL
 
Sub Mission Container (ภาชนะส่งตรวจ):
Plastic vial
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Specimen Type Temperature Time
Serum Refrigerated, 2oC to 8oC 7 days
Frozen, -20oC  3 months
 
 
 
Test Code (รหัสการทดสอบ):
GGT
Order Name (ชื่อการทดสอบ):
GGT (Gamma-Glutamyltransferase)
 
Method detail (วิธีการทดสอบ):
L-Gamma-glutamyl-3-carboxy-4-nitroanilide Substrate
 
Schedule (ตารางการทดสอบ):
Tested daily (24 hours)
 
Turnaround Time (ระยะเวลารอผล):
Collected specimen to report within 90 min
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
Chemistry, Laboratory Department Tel. 13224
 
Specimen Retention Time (ระยะเวลาเก็บสิ่งส่งตรวจ):
5 days
 
 
 
Test Code (รหัสการทดสอบ):
GGT
Order Name (ชื่อการทดสอบ):
GGT (Gamma-Glutamyltransferase)
 
 
Clinical Information (ข้อมูลทางคลินิก):
Gamma-glutamyl transferase was first identified in kidney tissue. Even though renal tissue has the highest level of GGT, the enzyme present in serum appears to originate primarily from the hepatobiliary system, and GGT is elevated in many forms of liver disease. Elevations in GGT levels are seen earlier and are more pronounced than those with other liver enzymes in cases of obstructive jaundice and metastatic neoplasms. It may reach 5 to 30 times normal levels in intra- or post-hepatic biliary obstruction. Only moderate elevations in the enzyme level (2 to 5 times normal) are observed with infectious hepatitis: therefore, GGT measurements are less useful diagnostically than transaminase determinations with this condition.
 
Reference Value (ค่าอ้างอิง):
Male: 7– 65 U/L
Female: 7 – 50 U/L
 
Interpretation (การแปลผล):
An elevation of gamma-glutamyltransferase (GGT) activity is seen in any and all forms of liver disease, although the highest elevations are seen in intra- or posthepatic biliary obstruction. Elevated values can also indicate alcoholic cirrhosis or individuals who are heavy drinkers. The finding of increased GGT and alkaline phosphatase (ALP) activity is consistent with hepatobiliary disease. The finding of normal GGT activity and increased ALP activity is consistent with skeletal disease.
 
Clinical Reference (เอกสารอ้างอิง):
  1. Manufacturer’s reagent package insert, Architect® GTT2, Abbott Ireland, Diagnostics Division. Lisnamuck, Longford Co. Longford, Ireland, June 2022.
  2. http://www.mayomedicallaboratories.com (Retrieved: 01 Jan 2019)