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Overview
ข้อมูลทั่วไป Specimen
ข้อมูลสิ่งส่งตรวจ Performance
ข้อมูลการทดสอบ Clinical & Interpretation
ข้อมูลทางคลินิก
 
Test Code (รหัสการทดสอบ):
090-31-4045
Order Name (ชื่อการทดสอบ):
Gentamicin Level **
 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Turnaround Time (ระยะเวลารอผล):
24-48hrs. (1-2 official days)
 
Useful For (ประโยชน์การทดสอบ):
ติดตามระดับยา Gentamicin เพื่อการรักษา

The results obtained are used in the diagnosis and treatment of gentamicin overdose and in monitoring levels of gentamicin to help ensure appropriate therapy.
 
Methodology (วิธีการทดสอบ):
CMIA
 
 
 
Test Code (รหัสการทดสอบ):
090-31-4045
Order Name (ชื่อการทดสอบ):
Gentamicin Level **
 
Patient Preparation (การเตรียมตัวผู้ป่วย):
Follow the instruction of physician and pharmarcist
 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
Serum, minimum volume 1 mL
 
Sub Mission Container (ภาชนะส่งตรวจ):
Plastic vial
 
 
 
Test Code (รหัสการทดสอบ):
090-31-4045
Order Name (ชื่อการทดสอบ):
Gentamicin Level **
 
Schedule (ตารางการทดสอบ):
N/A **Sent Out to Ramathibodi
 
Turnaround Time (ระยะเวลารอผล):
24-48hrs. (1-2 official days)
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
Ramathibodi, Toxicology 
Referral Lab Services, Laboratory Department 14160-2
 
 
 
Test Code (รหัสการทดสอบ):
090-31-4045
Order Name (ชื่อการทดสอบ):
Gentamicin Level **
 
 
Clinical Information (ข้อมูลทางคลินิก):
Gentamicin is used in the treatment of serious infections involving aminoglycoside-sensitive organisms. Monitoring gentamicin concentration in serum or plasma, along with careful clinical assessment, is the most effective means of ensuring adequate therapy. Gentamicin concentration correlates better with antibacterial activity than dosage. A standard dose of gentamicin does not always yield a predictable concentration because the drug’s concentration also depends on the patient’s volume of distribution and on the drug elimination. These factors are influenced by the mode of administration, the volume of extracellular fluid, renal retention, and physiological changes during therapy. Gentamicin has a narrow range of safe and effective concentration. Exposure to high concentrations for a prolonged period may cause renal impairment or ototoxicity. Patients with impaired renal function should be monitored closely while on gentamicin therapy because nephrotoxicity caused by gentamicin may be difficult to distinguish from symptoms of underlying renal disease.

Note: The susceptibility of the infecting organism, the severity of the infection, and the general health of the patient should be considered when determining an adequate drug level for individual patients.
 
Reference Value (ค่าอ้างอิง):
Peak (Therapeutic 3-12 ug/mL , Toxic > 12 ug/mL) 
Trough (Therapeutic 2 ug/mL) 
 
Interpretation (การแปลผล):
Periodic measurements of both peak and trough concentrations of gentamicin are recommended to ensure adequate drug levels and prevent toxic side effects. The susceptibility of the infecting organism, the severity of the infection, and the general health of the patient should be considered when determining an adequate drug level for individual patients.
 
Clinical Reference (เอกสารอ้างอิง):
https://www.ramapatholab.com (Retrieved: 04 Jun 2024)

https://www.bumrungrad.com/Lab-Service-Guide/Labs/Gentamicin-Level (Retrieved: 04 Jun 2024)