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ข้อมูลทั่วไป Specimen
ข้อมูลสิ่งส่งตรวจ Performance
ข้อมูลการทดสอบ Clinical & Interpretation
ข้อมูลทางคลินิก

Test Code (รหัสการทดสอบ):

ANHBCM

Order Name (ชื่อการทดสอบ):

HBc IgM (Hepatitis B Core Antibody, IgM)

Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):

Blood/ Plain Blood (Red Top) 6 mL, 1 tube

Turnaround Time (ระยะเวลารอผล):

Collected specimen to report within 3 hours (180 mins)

Useful For (ประโยชน์การทดสอบ):

Detection of IgM antibody to hepatitis B core antigen (anti-HBc IgM) in human serum.
Indicated for use as an aid in the diagnosis of acute or recent hepatitis B viral infection.

Methodology (วิธีการทดสอบ):

Chemiluminescent Microparticle Immuno Assay (CMIA) ร่วมกับ Flexible protocol (Chemiflex

AliasesName (ชื่อเรียกอื่นๆ) :

Hepatitis B Core IgM Antibody
Anti-HBc IgM
HBV Core IgM Antibody

Test Code (รหัสการทดสอบ):

ANHBCM

Order Name (ชื่อการทดสอบ):

HBc IgM (Hepatitis B Core Antibody, IgM)

Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):

Blood/ Plain Blood (Red Top) 6 mL, 1 tube

Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):

Serum, minimum volume 1 mL

Sub Mission Container (ภาชนะส่งตรวจ):

Plastic vial

Rejection Criteria (เกณฑ์ปฏิเสธสิ่งส่งตรวจ):

Hemolysis: 4+ reject

Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):

Specimen Type	Temperature	Time
Serum (keep in original tube)	Refrigerated, 2^oC to 8^oC	8 hours
Serum	Refrigerated, 2^oC to 8^oC	7 days
Serum	Frozen, -20^oC	> 7 days

Test Code (รหัสการทดสอบ):

ANHBCM

Order Name (ชื่อการทดสอบ):

HBc IgM (Hepatitis B Core Antibody, IgM)

Method detail (วิธีการทดสอบ):

Chemiluminescent Microparticle Immuno Assay (CMIA) ร่วมกับ Flexible protocol (Chemiflex

Schedule (ตารางการทดสอบ):

Tested daily (24 hours)

Turnaround Time (ระยะเวลารอผล):

Collected specimen to report within 3 hours (180 mins)

Performing Location (หน่วยงานที่ทำการทดสอบ):

Immunology, Laboratory Department Tel. 13227

Specimen Retention Time (ระยะเวลาเก็บสิ่งส่งตรวจ):

5 days

Test Code (รหัสการทดสอบ):

ANHBCM

Order Name (ชื่อการทดสอบ):

HBc IgM (Hepatitis B Core Antibody, IgM)

Clinical Information (ข้อมูลทางคลินิก):

Viral specific IgM antibody has been detected in most acute viral infections and is a reliable marker of acute disease. The concentrations of anti-HBc IgM rise rapidly in patients with acute infection; high levels of anti-HBc IgM have been detected in patients with acute hepatitis B viral infection. Hepatitis B surface antigen
(HBsAg) will generally also be present as a serological marker of an acute infection, but there are reports of HBsAg being undetectable.

In the convalescent phase, anti-HBc IgM will persist after the disappearance of HBsAg and decrease slowly over time. In the absence of information about any other hepatitis B virus (HBV) markers, it must be considered that an individual with detectable levels of anti-HBc IgM may be actively infected with HBV or that the infection may have resolved. Anti-HBc IgM may also be present in patients with chronic hepatitis B viral infection. The concentrations are generally lower than those associated with acute infections and may rise and fall with exacerbation of the disease. 5 Differentiation of acute and chronic hepatitis B viral infection solely on the basis of viral markers, which are also frequently present, such as HBsAg, anti-HBs, HBeAg, anti-HBe,
and anti-HBc, is difficult because most of these markers occur in both acute and chronic disease. Since there is high correlation of high antiHBc IgM concentrations with acute hepatitis B viral infection, the test for anti-HBc IgM may serve as an aid to distinguish acute hepatitis illness due to HBV versus superimposed infections by other possible agents such as hepatitis A, hepatitis C, or delta virus.

Reference Value (ค่าอ้างอิง):

Non reactive

Clinical Reference (เอกสารอ้างอิง):

Manufacturer’s reagent package insert, Architect Anti-HBc IgM, December 2017, Abbott GmbH & Co. KG, Max-Planck-Ring 2, Wiesbaden, Germany.