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Clear
Overview
ข้อมูลทั่วไป Specimen
ข้อมูลสิ่งส่งตรวจ Performance
ข้อมูลการทดสอบ Clinical & Interpretation
ข้อมูลทางคลินิก
 
Test Code (รหัสการทดสอบ):
090-30-2803
Order Name (ชื่อการทดสอบ):
IL-6 (Interleukin-6)
 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Turnaround Time (ระยะเวลารอผล):
Specimen collected to report within 3 hours
 
Useful For (ประโยชน์การทดสอบ):
Use to aid in the management of critically ill patients as early indicator for acute inflammation.
 
Methodology (วิธีการทดสอบ):
The electrochemiluminescence immunoassay  (ECLIA) method
 
AliasesName (ชื่อเรียกอื่นๆ) :
IL - 6 (Interleukin - 6)
IL-6
Interleukin
 
 
 
Test Code (รหัสการทดสอบ):
090-30-2803
Order Name (ชื่อการทดสอบ):
IL-6 (Interleukin-6)
 
Patient Preparation (การเตรียมตัวผู้ป่วย):
N/A
 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
Serum, minimum volume 0.5 mL
 
Sub Mission Container (ภาชนะส่งตรวจ):
Plastic tube
 
Rejection Criteria (เกณฑ์ปฏิเสธสิ่งส่งตรวจ):
Hemolysis: 4+ reject
 
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Specimen Type Temperature Time
Serum  Refrigerated, 2oC to 8oC 1 day
Freeze, -20oC 3 months
 20oC to 25oC  5 hours
 
 
 
Test Code (รหัสการทดสอบ):
090-30-2803
Order Name (ชื่อการทดสอบ):
IL-6 (Interleukin-6)
 
Method detail (วิธีการทดสอบ):
The electrochemiluminescence immunoassay  (ECLIA) method
 
Schedule (ตารางการทดสอบ):
Tested Daily (24 Hours)
 
Turnaround Time (ระยะเวลารอผล):
Specimen collected to report within 3 hours
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
Immunology, Laboratory Department Tel. 13227
 
Specimen Retention Time (ระยะเวลาเก็บสิ่งส่งตรวจ):
5 days
 
 
 
Test Code (รหัสการทดสอบ):
090-30-2803
Order Name (ชื่อการทดสอบ):
IL-6 (Interleukin-6)
 
 
Clinical Information (ข้อมูลทางคลินิก):
1. Interleukin‑6 (IL‑6) is a pleiotropic cytokine with a wide range of functions. It was first described as interferon‑β2, plasmacytoma growth factor, and hepatocyte stimulating factor. Later on it was described as human B‑cell‑stimulating factor 2 (BSF2). In 1988 it was proposed to name it IL‑6 as further studies had demonstrated that the protein shows activities not only on B‑cells but also on T‑cells, hematopoietic stem cells, hepatocytes and brain cells.
2. IL‑6 is produced from a single gene encoding a product of 212 amino acids, which is cleaved at the N‑terminus to produce a 184 amino acid peptide with a molecular weight between 22‑27 kDa. In 1989 it was reported that also immunoreactive complexes in the range of 60‑70 kDa were detected in human body fluids in patients with acute bacterial infections.
3. IL‑6 production is rapidly induced in the course of acute inflammatory reactions associated with injury, trauma, stress, infection, brain death, neoplasia, and other situations. IL‑6 concentrations in trauma patients may predict later complications from additional surgical stress or indicate missed injuries or complications. Sequential measurements of IL‑6 in serum or plasma of patients admitted to the ICU (intensive care unit) showed to be useful in evaluating the severity of SIRS (systemic inflammatory response syndrome), sepsis and
septic shock and to predict the outcome of these patients.
4. IL‑6 is also useful as an early alarm marker for the detection of neonatal sepsis. IL‑6 also plays a role in chronic inflammation e.g. rheumatoid arthritis.
 
Reference Value (ค่าอ้างอิง):
0 - 7 pg/mL
 
Clinical Reference (เอกสารอ้างอิง):
Manufacturer’s Reagent package insert, Elecsys IL- 6, Roche Diagnostics GmbH, D-68305 Mannheim.