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Overview
ข้อมูลทั่วไป Specimen
ข้อมูลสิ่งส่งตรวจ Performance
ข้อมูลการทดสอบ Clinical & Interpretation
ข้อมูลทางคลินิก

Test Code (รหัสการทดสอบ):

090-71-5520

Order Name (ชื่อการทดสอบ):

INVITAE Multi-Cancer Panel (Diagnostic test) **

Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):

Blood/ K3 EDTA (Lavender Top) 6 mL, 1 tube

Document Required:
Completed Requesition Form (Select Multi-Cancer Panel) LAB-REQ04-Rev01-0206_INVITAE-Diagnostics.pdf
& Completed Consent Form LAB-08170-Rev04-EN-Consent-for-Genomic-Medicine-Testing.pdf

Turnaround Time (ระยะเวลารอผล):

30 days

Useful For (ประโยชน์การทดสอบ):

This panel may be considered for individuals with:

a personal or family history presenting with multiple cancer types that could fit the features of more than one hereditary cancer syndrome
a clinical history indicative of a hereditary cancer syndrome but a limited pedigree due to small family size or adoption

There are also some common general features suggestive of a family with a hereditary cancer syndrome. These include:

cancer diagnosed at an unusually young age
different types of cancer that have occurred independently in the same person
cancer that has developed in both organs of a set of paired organs (e.g., both kidneys, both breasts)
several close blood relatives that have the same type of cancer
unusual cases of a specific cancer type (e.g., male breast cancer)

Methodology (วิธีการทดสอบ):

Next-generation sequencing (NGS)

AliasesName (ชื่อเรียกอื่นๆ) :

INVITAE 1 Panel Genetic Testing (Diagnostic test)

Test Code (รหัสการทดสอบ):

090-71-5520

Order Name (ชื่อการทดสอบ):

INVITAE Multi-Cancer Panel (Diagnostic test) **

Patient Preparation (การเตรียมตัวผู้ป่วย):

Genetics Counseling

Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):

Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):

Blood/ K3 EDTA (Lavender Top) 6 mL, 1 tube

Sub Mission Container (ภาชนะส่งตรวจ):

Whole blood EDTA, minimum volume 6 mL

Rejection Criteria (เกณฑ์ปฏิเสธสิ่งส่งตรวจ):

Hemolyzed or clotted blood
Blood (or saliva) from patients who have had an allogeneic (non-self donor) bone marrow transplant
Blood (or saliva) from patients who have had an allogeneic (non-self donor) stem cell transplant
Blood (or saliva) from patients who had a blood transfusion less than two weeks prior to specimen collection

Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):

Specimen Type	Temperature	Time
Whole blood EDTA	Refrigerated, 2^oC to 8^oC	14 days
Saliva (2mL) in special collection kit *	Ambient	30 days

* Optional, Nurse can request the special collection kit from Lab 13th Floor, Tel. 14160-2
** Sending to USA

Test Code (รหัสการทดสอบ):

090-71-5520

Order Name (ชื่อการทดสอบ):

INVITAE Multi-Cancer Panel (Diagnostic test) **

Method detail (วิธีการทดสอบ):

Next-generation sequencing (NGS)

Schedule (ตารางการทดสอบ):

N/A **Sent out to INVITAE, USA

Turnaround Time (ระยะเวลารอผล):

30 days

Performing Location (หน่วยงานที่ทำการทดสอบ):

INVITAE, USA
Referral Lab Services, Laboratory Department 14160-2

Test Code (รหัสการทดสอบ):

090-71-5520

Order Name (ชื่อการทดสอบ):

INVITAE Multi-Cancer Panel (Diagnostic test) **

Clinical Information (ข้อมูลทางคลินิก):

The Invitae Multi-Cancer Panel analyzes genes associated with hereditary cancers across major organ systems, including:

breast and gynecologic (breast, ovarian, uterine)
gastrointestinal (colorectal, gastric, pancreatic)
endocrine (thyroid, paraganglioma/pheochromocytoma, parathyroid, pituitary)
genitourinary (renal/urinary tract, prostate)
skin (melanoma, basal cell carcinoma)
brain/nervous system
sarcoma
hematologic (myelodysplastic syndrome/leukemia)

The Invitae Multi-Cancer Panel is designed to maximize diagnostic yield for individuals with a personal or family history of mixed cancers affecting multiple organ systems.

Genetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. Identification of a disease-causing variant would also guide testing and diagnosis of at-risk relatives. This test is specifically designed for heritable germline mutations and is not appropriate for the detection of somatic mutations in tumor tissue.

PTEN: Deletion/duplication analysis covers the promoter region.

Reference Value (ค่าอ้างอิง):

An interpretive report will be provided.

Clinical Reference (เอกสารอ้างอิง):