Home Lab Services Guide Tests

BROWSE BY TEST NAME

Clear

Overview
ข้อมูลทั่วไป Specimen
ข้อมูลสิ่งส่งตรวจ Performance
ข้อมูลการทดสอบ Clinical & Interpretation
ข้อมูลทางคลินิก

Test Code (รหัสการทดสอบ):

092-10-0076

Order Name (ชื่อการทดสอบ):

Kidney screen report (WES add-on panel)

Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):

Specimen/ Not required

Document required:
1. Consent for Genetic Testing (LAB-08171)
2. Requisition form

Turnaround Time (ระยะเวลารอผล):

Reported within 2 weeks

Useful For (ประโยชน์การทดสอบ):

•Individuals who have a family or personal history of certain Kidney Disease.
•Healthy people who are interested to know about the risk of your body’s predisposition for developing certain Kidney Disease.

Methodology (วิธีการทดสอบ):

Data analysis using Whole Exome Sequencing (WES) data

Test List In Profile (การทดสอบใน Profile):

1. Kidney screen report

AliasesName (ชื่อเรียกอื่นๆ) :

whole exome sequencing, WES, Kidney

Test Code (รหัสการทดสอบ):

092-10-0076

Order Name (ชื่อการทดสอบ):

Kidney screen report (WES add-on panel)

Patient Preparation (การเตรียมตัวผู้ป่วย):

Patient must has Whole exome sequencing (WES) before order this test

Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):

Specimen/ Not required

Document required:
1. Consent for Genetic Testing (LAB-08171)
2. Requisition form

Test Code (รหัสการทดสอบ):

092-10-0076

Order Name (ชื่อการทดสอบ):

Kidney screen report (WES add-on panel)

Turnaround Time (ระยะเวลารอผล):

Reported within 2 weeks

Performing Location (หน่วยงานที่ทำการทดสอบ):

Research and Development laboratory, Tel 14252

Test Code (รหัสการทดสอบ):

092-10-0076

Order Name (ชื่อการทดสอบ):

Kidney screen report (WES add-on panel)

Clinical Information (ข้อมูลทางคลินิก):

Kidney disease is a worldwide public health problem. Understanding the differences between acute kidney injury (AKI) and chronic kidney disease (CKD) is crucial for proper diagnosis and management. AKI typically develops rapidly, often over a few hours to a few days. On the other hand, CKD progresses slowly over three months to years and is characterized by the gradual loss of kidney function. CKD can be caused by various factors such as diabetes, hypertension, autoimmune diseases, and genetic predispositions.
Monogenic diseases are estimated to account for 70% and 10–15% of the overall prevalence of end-stage kidney disease (ESKD) in children and adults, respectively. Therefore, early detection of a monogenic cause for CKD can have important implications for patients and their family members, for instance in terms of management, prognosis, genetic counselling and screening of at-risk family members.

Clinical Reference (เอกสารอ้างอิง):

1. Knoers N, Antignac C, Bergmann C, et al. Genetic testing in the diagnosis of chronic kidney disease: recommendations for clinical practice. Nephrol Dial Transplant. 2022;37(2):239-254. doi:10.1093/ndt/gfab218
2. Levey AS, Eckardt KU, Tsukamoto Y, et al. Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int. 2005;67(6):2089-2100. doi:10.1111/j.1523-1755.2005.00365.x
3. Stokman MF, Renkema KY, Giles RH, Schaefer F, Knoers NV, Van Eerde AM. The expanding phenotypic spectra of kidney diseases: insights from genetic studies. Nature Reviews Nephrology. 2016 Aug;12(8):472-83.