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HomeLab Services GuideTests
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Overview
ข้อมูลทั่วไป Specimen
ข้อมูลสิ่งส่งตรวจ Performance
ข้อมูลการทดสอบ Clinical & Interpretation
ข้อมูลทางคลินิก
 
Test Code (รหัสการทดสอบ):
SHBG
Order Name (ชื่อการทดสอบ):
SHBG (Sex Hormone Binding Globulin)
 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain Blood (Red Top) 6 mL, 1 tube
 
Turnaround Time (ระยะเวลารอผล):
Specimen collected to reported within 2 hours
 
Useful For (ประโยชน์การทดสอบ):
  • Determination of sex hormone binding globulin (SHBG) in human serum.
  • Used as an aid in the diagnosis of androgen disorders.
 
Methodology (วิธีการทดสอบ):
Chemiluminescent Microparticle Immuno Assay (CMIA)
 
AliasesName (ชื่อเรียกอื่นๆ) :
Sex Hormone Binding Globulin
SHBG 
 
 
 
Test Code (รหัสการทดสอบ):
SHBG
Order Name (ชื่อการทดสอบ):
SHBG (Sex Hormone Binding Globulin)
 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain Blood (Red Top) 6 mL, 1 tube
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
Serum, minimum volume 1 mL
 
Sub Mission Container (ภาชนะส่งตรวจ):
Plastic vial
 
Rejection Criteria (เกณฑ์ปฏิเสธสิ่งส่งตรวจ):
Hemolysis: 4+ reject
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Specimen Type Temperature Time
Serum (keep in original tube) Refrigerated, 2oC to 8oC 8 hours
Serum Refrigerated, 2oC to 8oC 8 days
Frozen, -20oC 3 months
 
 
 
Test Code (รหัสการทดสอบ):
SHBG
Order Name (ชื่อการทดสอบ):
SHBG (Sex Hormone Binding Globulin)
 
Method detail (วิธีการทดสอบ):
Chemiluminescent Microparticle Immuno Assay (CMIA)
 
Schedule (ตารางการทดสอบ):
Tested Daily (24 Hours)
 
Turnaround Time (ระยะเวลารอผล):
Specimen collected to reported within 2 hours
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
Immunology, Laboratory Department Tel. 13227
 
Specimen Retention Time (ระยะเวลาเก็บสิ่งส่งตรวจ):
5 days
 
 
 
Test Code (รหัสการทดสอบ):
SHBG
Order Name (ชื่อการทดสอบ):
SHBG (Sex Hormone Binding Globulin)
 
 
Clinical Information (ข้อมูลทางคลินิก):
Sex hormone binding globulin (SHBG) is a glycoprotein of about 80-100 kDa; it has a high affinity for 17 beta-hydroxysteroid hormones such as testosterone and estradiol. SHBG concentration in plasma is regulated by, amongst other things, androgen/estrogen balance, thyroid hormones, insulin and dietary factors. It is the most important transport protein for estrogens and androgens in peripheral blood. SHBG concentration is a major factor regulating their distribution between the protein-bound and free states. Plasma SHBG concentrations are affected by a number of different diseases, high values being found in hyperthyroidism, hypogonadism, androgen insensitivity and hepatic cirrhosis in men. Low concentrations are found in myxoedema, hyperprolactinaemia and syndromes of excessive androgen activity. Measurement of SHBG is useful in the evaluation of mild disorders of androgen metabolism and enables identification of those women with hirsutism who are more likely to respond to estrogen therapy. The ratio of testosterone to SHBG is also known as the Free Androgen Index (FAI) or the Free Testosterone Index (FTI). This ratio correlates well
with both measured and calculated values of free testosterone and helps to discriminate subjects with excessive androgen activity from normal individuals.
 
Reference Value (ค่าอ้างอิง):
Sex Reference value Unit
Male 17.1 - 77.6 nmol/L
Female (Premenopausal) 34.3 - 147.7 nmol/L
Female (Postmenopausal) 26.4 - 118.0 nmol/L
 
Clinical Reference (เอกสารอ้างอิง):
Manufacturer’s Reagent package insert Architect SHBG, Abbott GmbH & Co. KG, Max-Planck-Ring 2, 65205 Wiesbaden, Germany.