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ข้อมูลทั่วไป Specimen
ข้อมูลสิ่งส่งตรวจ Performance
ข้อมูลการทดสอบ Clinical & Interpretation
ข้อมูลทางคลินิก

Test Code (รหัสการทดสอบ):

090-31-2860-01

Order Name (ชื่อการทดสอบ):

Vasoactive Intestinal Polypeptide (VIP) **

Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):

Blood/ K3 EDTA (Lavender Top) 3 mL, 3 tubes

Turnaround Time (ระยะเวลารอผล):

21 days (official days)

Useful For (ประโยชน์การทดสอบ):

Detection of vasoactive intestinal polypeptide producing tumors in patients with chronic diarrheal diseases.

Methodology (วิธีการทดสอบ):

Direct ELISA

Test Code (รหัสการทดสอบ):

090-31-2860-01

Order Name (ชื่อการทดสอบ):

Vasoactive Intestinal Polypeptide (VIP) **

Patient Preparation (การเตรียมตัวผู้ป่วย):

The patient should fast for 10 to 12 hours prior to collection of specimen. Patient should not be on any antacid medications or medications that affect intestinal motility for at least 48 hours prior to collection.

Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):

Blood/ K3 EDTA (Lavender Top) 3 mL, 3 tubes

Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):

Plasma EDTA, minimum volume 1 mL x 2 tube
Centrifuge and freeze immediately.

Sub Mission Container (ภาชนะส่งตรวจ):

Plastic tube

Rejection Criteria (เกณฑ์ปฏิเสธสิ่งส่งตรวจ):

Gross hemolysis	Reject
Gross lipemia	Reject
Gross icterus	OK

Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):

Specimen Type	Temperature	Time
Plasma EDTA	Frozen	90 days

Test Code (รหัสการทดสอบ):

090-31-2860-01

Order Name (ชื่อการทดสอบ):

Vasoactive Intestinal Polypeptide (VIP) **

Method detail (วิธีการทดสอบ):

Direct ELISA

Schedule (ตารางการทดสอบ):

N/A **Sent out to MAYO, USA

Turnaround Time (ระยะเวลารอผล):

21 days (official days)

Performing Location (หน่วยงานที่ทำการทดสอบ):

MAYO Laboratory
Referral Lab Services, Laboratory Department 14160-2

Test Code (รหัสการทดสอบ):

090-31-2860-01

Order Name (ชื่อการทดสอบ):

Vasoactive Intestinal Polypeptide (VIP) **

Clinical Information (ข้อมูลทางคลินิก):

Vasoactive intestinal polypeptide (VIP) was originally isolated from porcine small intestine and was recognized by its potent vasodilator activity. This brain/gut hormone has widespread distribution and is present in neuronal cell bodies localized in the central nervous system, digestive, respiratory, and urogenital tracts, and exocrine, thyroid, and adrenal glands. VIP has a wide scope of biological actions. The main effects of VIP include relaxation of smooth muscle (bronchial and vascular dilation), stimulation of gastrointestinal water and electrolyte secretion, and release of pancreatic hormones.

VIP-producing tumors (VIPomas) are rare; most (90%) are located in the pancreas. Watery diarrhea, hypokalemia, and achlorhydria are key symptoms.

Interpretation (การแปลผล):

Values above 75 pg/mL may indicate the presence of an enteropancreatic tumor causing hypersecretion of vasoactive intestinal polypeptide (VIP).
Values above 200 pg/mL are strongly suggestive of VIP-producing tumors (VIPoma).
VIPoma is unlikely with a 24-hour stool volume below 700 mL.

Cautions: This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. A recommended time period before collection cannot be made because it will depend on the isotope administered, the dose given and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive samples received in the laboratory will be held and assayed after the radioactivity has sufficiently decayed. This will result in a test delay.