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ข้อมูลสิ่งส่งตรวจ Performance
ข้อมูลการทดสอบ Clinical & Interpretation
ข้อมูลทางคลินิก

Test Code (รหัสการทดสอบ):

VITD125OH

Order Name (ชื่อการทดสอบ):

Vitamin D 1,25-Dihydroxy (MAYO Lab-USA) **

Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):

Blood/ Plain blood (Red top) 6 mL, 2 tubes

Turnaround Time (ระยะเวลารอผล):

Received specimen to report within 14 days

Useful For (ประโยชน์การทดสอบ):

As a second-order test in the assessment of vitamin D status, especially in patients with renal disease

Investigation of some patients with clinical evidence of vitamin D deficiency (eg, vitamin D-dependent rickets due to hereditary deficiency of renal 1-alpha hydroxylase or end-organ resistance to 1,25-dihydroxyvitamin D)

Differential diagnosis of hypercalcemia

Methodology (วิธีการทดสอบ):

Extraction/Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Test Code (รหัสการทดสอบ):

VITD125OH

Order Name (ชื่อการทดสอบ):

Vitamin D 1,25-Dihydroxy (MAYO Lab-USA) **

Patient Preparation (การเตรียมตัวผู้ป่วย):

Fasting (4-hour preferred but not required)

Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):

Blood/ Plain blood (Red top) 6 mL, 2 tubes

Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):

Serum, minimum volume 1.5 mL per tube

Sub Mission Container (ภาชนะส่งตรวจ):

Plastic tube

Rejection Criteria (เกณฑ์ปฏิเสธสิ่งส่งตรวจ):

Gross hemolysis	Reject
Gross lipemia	OK
Gross icterus	OK

Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):

Specimen Type	Temperature	Time
Serum	Refrigerated, 2^oC to 8^oC (preferred)	7 days
	Ambient	7 days
	Frozen	28 days

Test Code (รหัสการทดสอบ):

VITD125OH

Order Name (ชื่อการทดสอบ):

Vitamin D 1,25-Dihydroxy (MAYO Lab-USA) **

Method detail (วิธีการทดสอบ):

Extraction/Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Schedule (ตารางการทดสอบ):

N/A **Sent out to MAYO, USA

Turnaround Time (ระยะเวลารอผล):

Received specimen to report within 14 days

Performing Location (หน่วยงานที่ทำการทดสอบ):

MAYO Laboratory
Referral Lab Services, Laboratory Department 14160-2

Test Code (รหัสการทดสอบ):

VITD125OH

Order Name (ชื่อการทดสอบ):

Vitamin D 1,25-Dihydroxy (MAYO Lab-USA) **

Clinical Information (ข้อมูลทางคลินิก):

Vitamin D is a generic designation for a group of fat-soluble, structurally similar sterols, which act as hormones. In the presence of renal disease or hypercalcemia, testing of 1,25-dihydroxy vitamin D (DHVD) might be needed to adequately assess vitamin D status. The 25-hydroxyvitamin D (25HDN) test (25HDN / 25-Hydroxyvitamin D2 and D3, Serum) in serum is otherwise the preferred initial test for assessing vitamin D status and most accurately reflects the body's vitamin D stores.

Advisory Information: The 25-hydroxyvitamin D test (25-Hydroxyvitamin D2 and D3, Serum) in serum the preferred initial test for assessing vitamin D status and most accurately reflects the body's vitamin D stores. In the presence of renal disease or hypercalcemia, testing of 1,25-dihydroxy vitamin D (DHVD) might be needed to adequately assess vitamin D status.

Reference Value (ค่าอ้างอิง):

Males:
<16 years: 24-86 pg/mL
> or =16 years: 18-64 pg/mL

Females:
<16 years: 24-86 pg/mL
> or =16 years: 18-78 pg/mL

Interpretation (การแปลผล):

1,25-Dihydroxyvitamin D (DVHD) concentrations are low in chronic renal failure and hypoparathyroidism.

DVHD concentrations are high in sarcoidosis and other granulomatous diseases, some malignancies, primary hyperparathyroidism, and physiologic hyperparathyroidism.

DVHD concentrations are not a reliable indicator of vitamin D toxicity; normal (or even low) results may be seen in such cases.

Clinical Reference (เอกสารอ้างอิง):