Test Code (รหัสการทดสอบ):
090-70-1441
Order Name (ชื่อการทดสอบ):
Zika, Dengue, Chikungunya Virus, Multiplex Real time RT-PCR
Clinical Information (ข้อมูลทางคลินิก):
Arboviruses are transmitted by arthropods, including those responsible for the current pandemic, flaviviruses (Dengue, Zika, Yellow Fever and West Nile, etc) and alphavirus (Chikungunya, Mayaro and Ross River, etc).These viruses are transmitted by Aedes mosquitoes, especially Aedes albopictus and Aedes aegypti are the presumed vector. The illnesses caused by arbovirus have similar clinical presentation with prominent fever, headache, rash, vomiting, fatigue, myalgias (muscle aches), arthralgias (joint aches) and other unspecific illnesses can be observed.
Arbovirus infections are difficult to diagnose, especially during the early stages. It can be confused with severe malaria, dengue hemorrhagic fever, leptospirosis, viral hepatitis, other hemorrhagic fevers, (Bolivian, Argentine and Venezuelan hemorrhagic fevers as well as other Flaviviridae such as the West Nile and Zika viruses) and other diseases, as well as poisoning. Therefore, to be recognize and distinguish them promptly are required in order to treat in time and to prevent further spread and recurrence of their infections.
Reference Value (ค่าอ้างอิง):
Zika, PCR Not detected
Dengue, PCR Not detected
Chikungunya, PCR Not detected
Interpretation (การแปลผล):
1. Viral nucleic acid may not be detected in plasma specimen after 7 days of the onset of symptoms. After this time, serologic testing is recommended for diagnosis of the infection.
2. The detection result is dependant upon proper sample specimen collection, handling, transportation, storage, and preparation, including extraction.
3.All results from this tests must be correlated with the clinical history, epidemiological data and other data available to the clinician evaluating the patient.
4. As with other tests, negative results do not rule out dengue virus infections.
5. False-negative results may occur when the infecting organism has genomic mutations, insertions, deletions, or rearrangements or when performed very early in the course of illness.
6. False-negative results may occur if inadequate numbers of organisms are present in the specimen due to improper collection, transport or handling.
Clinical Reference (เอกสารอ้างอิง):
Manufacturer’s packages insert, STANDARD™ Arbovirus Panel, April 2023, SD Biosensor Inc, Chungcheongbuk-do 27915, Korea.