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Transarterial Chemoembolization (TACE)

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Transarterial chemoembolization (TACE) is the administration of a chemotherapeutic agent through an artery directly to a cancerous tumor in the liver, followed by the embolization of the blood vessels feeding the cancerous tumor, causing interruption of blood. This is a palliative treatment for patients not eligible for surgery. However, a portion of viable cancer cells may remain and new feeding vessels can grow from surrounding tissue. Therefore, it is necessary to undergo repeated sessions at 6- to 8-week intervals to eliminate the remaining cancer cells.

Indications
  • Patients with a progressive large-sized tumor or multiple tumors.
  • When surgery is not possible due to insufficient post-operative functional liver.
  • The need to pre-operatively decrease the tumor size for patients awaiting liver surgery or transplantation.
  • Palliative treatment.
  • Patients with poor liver disease assessment.
  • Patients with portal vein thrombosis.
  • Extrahepatic metastasis affecting the survival rates of patients.
  • Extensive liver involvement of the cancerous tumor more than 50%.
  • Patients with a history of severe contrast allergy.
  • Bruising or hematoma at the puncture site.
  • Nausea, vomiting, and low fever occur about 40-50% of the time and usually during the first 2-3 days. These symptoms normally go away on their own after 1-2 weeks.
  • Ascites, liver abscess and bloodstream infection, which are rare.
After you are discharged, it is recommended that you stay at a hotel close to the hospital for at least one day for convenience in traveling to hospital if any complications arise after the procedure.
 
Last modify: April 25, 2023

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